Sugi Predict

Sugi Predict / Compounds / SCHEMBL1237496

SCHEMBL1237496

SCHEMBL1237496

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nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.50
▸ MAPT P10636 1/20 0.50
▸ PTGS1 P23219 1/20 0.50
▸ SLC1A2 P43004 4/20 0.35
▸ SLC1A1 P43005 4/20 0.35
▸ SLC1A3 P43003 3/20 0.35
▸ SLC7A5 Q01650 2/20 0.34
▸ GRIK1 P39086 5/20 0.34
▸ GRIK2 Q13002 3/20 0.34
▸ HMGCR P04035 1/20 0.33
▸ CHRM1 P11229 1/20 0.33
▸ TBXA2R P21731 1/20 0.33
▸ ADRA1A P35348 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ KIF11 P52732 1/20 0.33
▸ DPP4 P27487 1/20 0.32
▸ GRIA4 P48058 1/20 0.32
▸ GRIK3 Q13003 1/20 0.32
▸ GRIK5 Q16478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1237494 1.00 ALDH1A1 (0.50) ALDH1A1MAPTPTGS1SLC1A2SLC1A1
SCHEMBL1236209 0.81 ALDH1A1 (0.50) ALDH1A1MAPTPTGS1SLC1A2SLC1A1
SCHEMBL1236211 0.81 ALDH1A1 (0.50) ALDH1A1MAPTPTGS1SLC1A2SLC1A1
SCHEMBL3165156 0.80 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1HMGCRCHRM1
SCHEMBL6130129 0.79 ALDH1A1 (0.48) ALDH1A1MAPTPTGS1SLC7A5HMGCR
SCHEMBL6130132 0.79 ALDH1A1 (0.48) ALDH1A1MAPTPTGS1SLC7A5HMGCR
SCHEMBL3821550 0.78 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1SLC1A2SLC1A1
SCHEMBL1631413 0.78 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1SLC1A2SLC1A1
SCHEMBL5288950 0.78 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1SLC1A2SLC1A1
SCHEMBL5598275 0.77 ALDH1A1 (0.46) ALDH1A1MAPTPTGS1SLC7A5GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116670151-A Antibacterial cyclic peptides targeting acinetobacter and other gram negative pathogens 犹他大学研究基金会 2023-08-29 — — CN claimed
CN-109988312-B Polyamide acid ester, preparation method, negative polyimide composition and application 深圳先进技术研究院 2023-04-11 — — CN claimed
CN-109988312-A A kind of poly amic acid ester, preparation method and negative polyimide composition and application 深圳先进技术研究院 2019-07-09 — — CN claimed
CN-109946925-A A kind of compound is promoting the application in polyimides low-temperature setting, polyimide precursor composition and application thereof 深圳先进技术研究院 2019-06-28 — — CN claimed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 — — US claimed
JP-56051989-A — — None — — JP disclosed
US-12516147-B2 Aldimines and uses thereof BOSTIK SA (FR) 2026-01-06 — — US disclosed
CN-119775350-A Cordyceps cyclopeptide compound separated from cordyceps militaris and application thereof 中国科学院微生物研究所 2025-04-08 — — CN disclosed
EP-4077273-B1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2025-04-02 — — EP disclosed
US-20250074945-A1 ANTIBACTERIAL CYCLOPEPTIDES TARGETING ACINETOBACTER AND OTHER GRAM-NEGATIVE PATHOGENS UNIV UTAH RES FOUND (US) 2025-03-06 — — US disclosed
US-12215129-B2 Antibacterial cyclopeptides targeting acinetobacter and other gram-negative pathogens UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-02-04 — — US disclosed
WO-2024096066-A1 CYCLIC PEPTIDE DERIVATIVE COMPOSITION FOR TREATING OR PREVENTING CENTRAL NERVOUS SYSTEM INJURY/DISEASE 第一工業製薬株式会社 2024-05-10 — — WO disclosed
EP-0167132-B1 PROCESS FOR PRODUCING L-ISOLEUCINE BY FERMENTATION AJINOMOTO CO., INC. (JP) 1992-01-02 — — EP disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 — — US disclosed
US-4656135-A USING BACTERIA RESISTANT TO KETOMALONIC ACID OR METHYLLYSINE AJINOMOTO CO., INC. (JP) 1987-04-07 — — US disclosed
EP-0073143-B1 NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES Ryan, James Walter (US) 1985-11-21 — — EP disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 — — EP disclosed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 — — EP disclosed
JP-S5651989-A PREPARATION OF L-VALINE BY FERMENTATION METHOD AJINOMOTO CO INC 1981-05-09 — — JP disclosed
JP-S05651989-A — — 0001-01-01 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074945-A1 ANTIBACTERIAL CYCLOPEPTIDES TARGETING ACINETOBACTER AND OTHER GRAM-NEGATIVE PATHOGENS DNPEP, PIN1, PPIA ALDH1A1 4762/4885MAPT 2726/4885PTGS1 3847/4885
US-12215129-B2 Antibacterial cyclopeptides targeting acinetobacter and other gram-negative pathogens DNPEP, PIN1, PPIA ALDH1A1 4762/4885MAPT 2726/4885PTGS1 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.