Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12375023 | 0.93 | THRB (0.44) | THRBKMT2AMAPTLMNAFFAR1 | |
| SCHEMBL12375057 | 0.93 | THRB (0.44) | THRBKMT2AMAPTLMNAFFAR1 | |
| SCHEMBL12375035 | 0.90 | THRB (0.47) | THRBKMT2AMAPTLMNAFFAR1 | |
| SCHEMBL12375046 | 0.86 | MAPT (0.38) | KMT2AMAPTKDM4ENPC1LMNA | |
| SCHEMBL12375024 | 0.85 | THRB (0.43) | THRBKMT2AMAPTFFAR4FFAR1 | |
| SCHEMBL16541707 | 0.85 | THRB (0.46) | THRBKMT2AMAPTLMNAFFAR1 | |
| SCHEMBL12375051 | 0.84 | PPARD (0.35) | THRBMAPTKDM4ENPC1LMNA | |
| SCHEMBL13963258 | 0.83 | AKR1B10 (0.38) | THRBKMT2AMAPTLMNAMAOA | |
| SCHEMBL12375045 | 0.83 | MAPT (0.41) | THRBKMT2AMAPTKDM4ENPC1 | |
| SCHEMBL12375027 | 0.81 | KMT2A (0.43) | THRBKMT2AMAPTLMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440101-B2 | Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same | DIC CORPORATION (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20110186776-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2011-08-04 | — | — | US | disclosed |