Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005607 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL12536073 | 0.72 | ADORA2A (0.46) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12376505 | 0.71 | — | — | |
| SCHEMBL12376542 | 0.69 | ADORA1 (0.45) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12376482 | 0.68 | — | — | |
| SCHEMBL12376462 | 0.68 | ADORA1 (0.30) | — | |
| SCHEMBL12376483 | 0.68 | KDM4E (0.46) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL12910802 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL12376472 | 0.67 | NPSR1 (0.32) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL12534753 | 0.65 | ADORA1 (0.44) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426602-B2 | Heteroaryl-substituted dicyanopyridines and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-23 | — | — | US | disclosed |
| US-20110207698-A1 | HETEROARYL-SUBSTITUTED DICYANOPYRIDINES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207698-A1 | HETEROARYL-SUBSTITUTED DICYANOPYRIDINES AND THEIR USE | QDPR, TNNI3, SDHA | KDM4E 3532/4885ALDH1A1 2170/4885HPGD 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.