SCHEMBL123765

SCHEMBL123765

N[C@@H](CC(=O)O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.59
GABBR1 Q9UBS5 1/20 0.59
KMT2A Q03164 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CYP2C19 P33261 1/20 0.53
SCN4A P35499 2/20 0.45
CYP2D6 P10635 1/20 0.44
SRC P12931 1/20 0.44
GRM2 Q14416 1/20 0.44
GRM3 Q14832 1/20 0.44
DPP4 P27487 2/20 0.44
F2 P00734 1/20 0.44
CPA1 P15085 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59840 1.00 GABBR2 (0.59) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
SCHEMBL288753 1.00 GABBR2 (0.59) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
Hydrochloric Acid SCHEMBL3874351 0.98 GABBR2 (0.57) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
Hydrochloric Acid SCHEMBL4150999 0.98 GABBR2 (0.57) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
SCHEMBL9386161 0.98 GABBR2 (0.57) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
Hydrochloric Acid SCHEMBL2934796 0.98 GABBR2 (0.57) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
Acetamide SCHEMBL27677566 0.92 GABBR2 (0.52) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
SCHEMBL7244087 0.90 GABBR2 (0.55) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
SCHEMBL5846637 0.89 KMT2A (0.49) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19
SCHEMBL5845485 0.89 KMT2A (0.49) GABBR2GABBR1KMT2ASMN1; SMN2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113880721-B Synthesis method of dapoxetine 湖南九典制药股份有限公司 2024-05-28 CN claimed
CN-114057917-A Post-treatment ashless dispersant and preparation method thereof 中国石油天然气股份有限公司 2022-02-18 CN claimed
CN-113880721-A Synthetic method of dapoxetine 湖南九典制药股份有限公司 2022-01-04 CN claimed
CN-107935868-A A kind of crystal form of 5 hydroxytryptamine reuptake inhibithors and preparation method thereof 广州白云山医药集团股份有限公司白云山制药总厂 2018-04-20 CN claimed
CN-103664660-B A kind of synthetic method of dapoxetine hydrochloride SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) 2015-09-09 CN claimed
CN-103664660-A Synthesis method of dapoxetine hydrochloride SUZHOU UUGENE BIOPHARMA CO LTD 2014-03-26 CN claimed
US-7015348-B2 Method for producing an optically active β-amino acid TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-03-21 US claimed
EP-0089886-A1 Process for the preparation of a free alpha-L-amino acid CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1983-09-28 EP claimed
EP-4591934-A2 VARIANTS OF C-TYPE NATRIURETIC PEPTIDE BioMarin Pharmaceutical Inc. (US) 2025-07-30 EP disclosed
EP-4523749-A2 VARIANTS OF C-TYPE NATRIURETIC PEPTIDE BioMarin Pharmaceutical Inc. (US) 2025-03-19 EP disclosed
CN-109790114-B Novel chiral ligand, metal chelate, various unnatural amino acids and synthesis method of maraviroc and key intermediate thereof 中国科学院上海药物研究所 2025-03-07 CN disclosed
CN-109790114-B Novel chiral ligand, metal chelate, various unnatural amino acids and synthesis method of maraviroc and key intermediate thereof 中国科学院上海药物研究所 2025-03-07 CN disclosed
US-12214015-B2 Use of c-type natriuretic peptide variants to treat osteoarthritis BIOMARIN PHARMACEUTICAL INC. (US) 2025-02-04 US disclosed
CN-118307428-B Chiral alpha unnatural amino acid and preparation method thereof by rare noble metal complex 北京元延医药科技股份有限公司 2025-01-10 CN disclosed
EP-0125299-A1 GLYCOSYLATED INSULIN DERIVATIVES. UNIV UTAH (US) 1984-11-21 EP disclosed
US-4483792-A SUCCINYL AND GUTARYL GLUCOSAMINES, LOWER BLOOD SUGAR UNIVERSITY OF UTAH 1984-11-20 US disclosed
US-4478830-A HYPOGLYCEMIC AGENTS UNIVERSITY OF UTAH 1984-10-23 US disclosed
US-4478746-A Glycosylated insulin derivatives UNIVERSITY OF UTAH 1984-10-23 US disclosed
WO-1984001896-A1 GLYCOSYLATED INSULIN DERIVATIVES UNIV UTAH (US) 1984-05-24 WO disclosed
US-4444683-A Glycosylated insulin derivatives UNIVERSITY OF UTAH (US) 1984-04-24 US disclosed