SCHEMBL12376657

SCHEMBL12376657

CCC(C)(CC)c1ccc(SC(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.44
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
AR P10275 1/20 0.33
ALDH1A1 P00352 1/20 0.32
EPHX2 P34913 1/20 0.30
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20661303 0.94 SLC6A4 (0.41) SLC6A4ESR1ESR2KDM4EHSD17B10
SCHEMBL14350840 0.89 RAB9A (0.45) SLC6A4ESR1ESR2KDM4EHSD17B10
SCHEMBL14350839 0.86 SRD5A2 (0.42) SLC6A4ESR1ESR2ALDH1A1EPHX2
SCHEMBL14350838 0.86 HSD11B1 (0.40) SLC6A4ESR1ESR2ALDH1A1
SCHEMBL14334716 0.85 ESR1 (0.40) SLC6A4ESR1ESR2ALDH1A1
SCHEMBL20661304 0.85 ESR1 (0.40) SLC6A4ESR1ESR2ALDH1A1
SCHEMBL12676694 0.83 NPC1 (0.44) SLC6A4KDM4EHSD17B10
SCHEMBL19114331 0.80 ESR1 (0.37) ESR1ESR2
SCHEMBL20457555 0.80 ESR1 (0.37) SLC6A4ESR1ESR2ALDH1A1
SCHEMBL19114811 0.80 ESR1 (0.37) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777130-B2 Polyphenylene sulfide microparticles TORAY INDUSTRIES, INC. (JP) 2017-10-03 US disclosed
US-7993792-B2 Polymer blocks for PEM applications GM Global Technology Operations LLC (US) 2011-08-09 US disclosed
US-20110081597-A1 POLYMER ELECTROLYTE, CROSSLINKED POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE AND USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-07 US disclosed