SCHEMBL12376953

SCHEMBL12376953

COc1ccc(C(C)c2ccc(OC(=O)c3ccc(C(C)=O)cc3)c(C)c2)cc1C

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
KMT2A Q03164 5/20 0.45
MAPT P10636 3/20 0.43
GAA P10253 2/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42
TAS1R3 Q7RTX0 5/20 0.41
TAS1R1 Q7RTX1 5/20 0.41
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12445365 0.96 ALDH1A1 (0.46) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL12376962 0.94 KMT2A (0.46) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL12677698 0.94 ALDH1A1 (0.47) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL13324834 0.93 ALDH1A1 (0.44) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL12762438 0.93 ALDH1A1 (0.44) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL12404366 0.92 KMT2A (0.47) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL19797769 0.91 MAPT (0.55) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL13324838 0.90 KMT2A (0.46) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL13324849 0.89 KMT2A (0.49) ALDH1A1KMT2AMAPTGAATP53
SCHEMBL12762424 0.89 MAPT (0.43) ALDH1A1KMT2AMAPTGAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-9684277-B2 Process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-20170060008-A1 IMAGE FORMING METHOD, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-03-02 US disclosed
US-9575422-B2 Method of producing electrophotographic photosensitive member, method of producing organic device, and emulsion for charge transporting layer CANON KABUSHIKI KAISHA (JP) 2017-02-21 US disclosed
US-9494882-B2 Method of producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2016-11-15 US disclosed
US-9436107-B2 Method of producing electrophotographic photosensitive member, and emulsion for a charge transporting layer CANON KABUSHIKI KAISHA (JP) 2016-09-06 US disclosed
US-20160154326-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-02 US disclosed
US-20160139556-A1 PROCESS CARTRIDGE AND IMAGE-FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2016-05-19 US disclosed
US-9341964-B2 Process for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 US disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-7718337-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-18 US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090081570-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-26 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-7473507-B2 Electrophotographic photoreceptor with polyester resin in photosensitive layer MITSUBISHI CHEMICAL CORPORATION (JP) 2009-01-06 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed