SCHEMBL12677698

SCHEMBL12677698

COc1ccc(C(C)c2ccc(OC(=O)c3ccc(Cc4ccc(C(C)=O)cc4)cc3)c(C)c2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
KMT2A Q03164 4/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
TAS1R3 Q7RTX0 6/20 0.40
TAS1R1 Q7RTX1 6/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 2/20 0.40
GAA P10253 2/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
TP53 P04637 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13324834 0.97 ALDH1A1 (0.44) ALDH1A1KMT2AL3MBTL1TAS1R3TAS1R1
SCHEMBL13324838 0.96 KMT2A (0.46) ALDH1A1KMT2AL3MBTL1TAS1R3TAS1R1
SCHEMBL12376953 0.94 ALDH1A1 (0.49) ALDH1A1KMT2ATAS1R3TAS1R1MAPT
SCHEMBL12445365 0.91 ALDH1A1 (0.46) ALDH1A1KMT2ATAS1R3TAS1R1MAPT
SCHEMBL12799825 0.89 TAS1R3 (0.43) ALDH1A1KMT2AL3MBTL1TAS1R3TAS1R1
SCHEMBL12903836 0.88 L3MBTL1 (0.47) ALDH1A1KMT2AL3MBTL1TAS1R3TAS1R1
SCHEMBL12376962 0.88 KMT2A (0.46) ALDH1A1KMT2AL3MBTL1TAS1R3TAS1R1
SCHEMBL12762438 0.87 ALDH1A1 (0.44) ALDH1A1KMT2AL3MBTL1TAS1R3TAS1R1
SCHEMBL12376952 0.86 KMT2A (0.49) ALDH1A1KMT2AL3MBTL1LMNAMAPT
SCHEMBL12404366 0.86 KMT2A (0.47) ALDH1A1KMT2ATAS1R3TAS1R1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed