SCHEMBL12376960

SCHEMBL12376960

COc1ccc(C2(c3ccc(OC(=O)c4ccc(Oc5ccc(C(C)=O)cc5)cc4)cc3)CCCCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.46
HPGD P15428 2/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 6/20 0.45
LMNA P02545 3/20 0.45
CYP2C9 P11712 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 3/20 0.43
GFER P55789 1/20 0.43
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ALDH1A1 P00352 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PARP10 Q53GL7 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12404396 1.00 MAPT (0.46) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL12345968 0.96 KMT2A (0.48) MAPTHPGDKMT2ALMNACYP2C9
SCHEMBL19863504 0.93 KMT2A (0.45) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL17066141 0.93 KMT2A (0.45) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL17370927 0.92 GAA (0.42) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL13656591 0.91 NPSR1 (0.45) MAPTHPGDKMT2ALMNACYP2C9
SCHEMBL14007589 0.90 NPSR1 (0.47) MAPTHPGDKMT2ALMNACYP2C9
SCHEMBL17131378 0.88 ADORA3 (0.51) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL139339 0.87 CA1 (0.57) MAPTHPGDKMT2ALMNACYP2C9
SCHEMBL13656590 0.87 NPSR1 (0.47) MAPTHPGDKMT2ALMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2799461-B1 POLYCARBONATE COPOLYMER, AND COATING LIQUID AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING SAME IDEMITSU KOSAN CO (JP) 2017-10-11 EP disclosed
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-9529284-B2 Process cartridge, image forming method, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-12-27 US disclosed
US-9529285-B2 Polycarbonate copolymer, and coating liquid and electrophotographic photosensitive body using same IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US disclosed
US-9529285-B2 Polycarbonate copolymer, and coating liquid and electrophotographic photosensitive body using same IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US disclosed
US-20160154325-A1 PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-02 US disclosed
US-9104124-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-08-11 US disclosed
US-9091912-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-07-28 US disclosed
US-8980509-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2015-03-17 US disclosed
US-20140363760-A1 POLYCARBONATE COPOLYMER, AND COATING LIQUID AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-12-11 US disclosed
US-20140051018-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-02-20 US disclosed
US-20130236823-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2013-09-12 US disclosed
US-20130202327-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-08-08 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed