SCHEMBL12376972

SCHEMBL12376972

CCOc1ccc(/C=C/c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.61
MAOB P27338 2/20 0.57
ESR1 P03372 2/20 0.54
AHR P35869 1/20 0.54
PTGS2 P35354 1/20 0.51
TUBB4A P04350 1/20 0.50
TUBB P07437 1/20 0.50
TUBA3C P0DPH7 1/20 0.50
TUBA1B P68363 1/20 0.50
TUBA4A P68366 1/20 0.50
TUBB4B P68371 1/20 0.50
TUBB3 Q13509 1/20 0.50
TUBB2A Q13885 1/20 0.50
TUBB8 Q3ZCM7 1/20 0.50
TUBA3E Q6PEY2 1/20 0.50
TUBA1A Q71U36 1/20 0.50
TUBA1C Q9BQE3 1/20 0.50
TUBB6 Q9BUF5 1/20 0.50
TUBB2B Q9BVA1 1/20 0.50
TUBB1 Q9H4B7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16489730 1.00 RELA (0.61) RELAMAOBESR1AHRPTGS2
SCHEMBL14665948 1.00 RELA (0.61) RELAMAOBESR1AHRPTGS2
SCHEMBL15499120 0.95 RELA (0.56) RELAMAOBESR1AHRPTGS2
SCHEMBL15496801 0.95 RELA (0.56) RELAMAOBESR1AHRPTGS2
SCHEMBL16604896 0.93 MAOB (0.55) RELAMAOBESR1AHRPTGS2
SCHEMBL16922633 0.87 AHR (0.56) RELAMAOBAHRPTGS2TUBB4A
SCHEMBL11033784 0.86 RELA (0.77) RELAMAOBESR1AHRPTGS2
SCHEMBL10866111 0.86 RELA (0.77) RELAMAOBESR1AHRPTGS2
SCHEMBL12376974 0.85 KDM4E (0.52) RELAMAOBESR1AHRNPC1
SCHEMBL15496803 0.84 RELA (0.51) RELAMAOBESR1AHRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056801-A1 Electrophotographic Photoreceptor, Electrophotographic Photoreceptor Cartridge, and Image Forming Device MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-23 US disclosed
US-20190025719-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR FOR POSITIVE CHARGING, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2019-01-24 US disclosed
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-9557660-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, charge transport layer forming coating liquid, and method for manufacturing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2017-01-31 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed