SCHEMBL12376989

SCHEMBL12376989

C(=C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccc(-c2ccc(-c3ccc(N(C=C(c4ccccc4)c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
HPGD P15428 3/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 4/20 0.34
NPC1 O15118 2/20 0.34
LMNA P02545 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
PTPN1 P18031 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
GSK3B P49841 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5036464 1.00 MEN1 (0.36) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL3966094 0.92 ALDH1A1 (0.41) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL13242019 0.89 CES2 (0.40) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17735845 0.89 CES2 (0.40) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL13242004 0.89 CES2 (0.40) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17735838 0.88 CES2 (0.43) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17735830 0.88 CES2 (0.39) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL16938084 0.88 CES2 (0.43) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL12377631 0.86 ALDH1A1 (0.41) KMT2AMAPTALDH1A1GAARAB9A
SCHEMBL14104304 0.86 CYP19A1 (0.42) MEN1KMT2AMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3415989-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2020-07-22 EP disclosed
US-10635009-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-28 US disclosed
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed