Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.34 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27169587 | 0.91 | PDK2 (0.41) | PDK2PGRCYP3A4AKR1A1AKR1B1 | |
| SCHEMBL31363013 | 0.84 | PDK2 (0.43) | PDK2PGRCYP3A4AKR1A1AKR1B1 | |
| SCHEMBL17686479 | 0.84 | PDK2 (0.43) | PDK2PGRHTR2AHTR2C | |
| SCHEMBL1922755 | 0.82 | PDK2 (0.52) | PDK2PGRCYP3A4AKR1A1AKR1B1 | |
| SCHEMBL26569241 | 0.80 | CRHR1 (0.37) | PDK2PGRAKR1A1AKR1B1SMN1; SMN2 | |
| SCHEMBL16435208 | 0.78 | PDK2 (0.48) | PDK2PGRCYP3A4AKR1A1AKR1B1 | |
| SCHEMBL30431586 | 0.76 | PDK2 (0.38) | PDK2PGRAKR1A1AKR1B1PPOX | |
| SCHEMBL28560786 | 0.76 | PDK2 (0.38) | PDK2PGRAKR1A1AKR1B1PPOX | |
| SCHEMBL16435207 | 0.74 | PDK2 (0.42) | PDK2PGRAKR1A1AKR1B1LMNA | |
| SCHEMBL3147109 | 0.74 | ALK (0.38) | PDK2CYP3A4LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691398-B2 | 4-aminofluorene compound and organic light emitting device | CANON KABUSHIKI KAISHA (JP) | 2014-04-08 | — | — | US | disclosed |
| US-8691398-B2 | 4-aminofluorene compound and organic light emitting device | CANON KABUSHIKI KAISHA (JP) | 2014-04-08 | — | — | US | disclosed |
| EP-1966124-B1 | 4-AMINOFLUORENE COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES | CANON KK (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7998597-B2 | Organic light emitting device | CANON KABUSHIKI KAISHA (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7998597-B2 | Organic light emitting device | CANON KABUSHIKI KAISHA (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20100033081-A1 | 4-AMINOFLUORENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100033081-A1 | 4-AMINOFLUORENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090302758-A1 | ORGANIC LIGHT EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090302758-A1 | ORGANIC LIGHT EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-12-10 | — | — | US | disclosed |
| WO-2007123259-A1 | ORGANIC LIGHT EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100033081-A1 | 4-AMINOFLUORENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE | ALAD, CYP4F12, CYP4F11 | PDK2 2280/4885NOTUM 2459/4885PGR 4403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.