Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25706219 | 0.82 | CISD1 (0.39) | MAPK1ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL12235606 | 0.80 | TDP2 (0.48) | MAPK1CYP1B1ALDH1A1LMNAMAPT | |
| SCHEMBL12235632 | 0.80 | CYP1B1 (0.58) | MAPK1CYP1B1ALDH1A1LMNAMAPT | |
| SCHEMBL21930007 | 0.79 | MAPK1 (0.47) | MAPK1CYP1B1ALDH1A1LMNAMAPT | |
| SCHEMBL20576762 | 0.79 | CYP1B1 (0.35) | MAPK1CYP1B1ALDH1A1LMNAMAPT | |
| SCHEMBL23665440 | 0.77 | EP300 (0.40) | MAPK1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL20369502 | 0.76 | HTR2A (0.39) | MAPK1ALDH1A1LMNAELANEKMT2A | |
| SCHEMBL20369482 | 0.76 | HTR2A (0.39) | MAPK1ALDH1A1LMNAELANEKMT2A | |
| SCHEMBL12235769 | 0.75 | F2 (0.46) | MAPK1CYP1B1ALDH1A1LMNAMAPT | |
| SCHEMBL12235615 | 0.74 | LMNA (0.51) | MAPK1CYP1B1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11932616-B2 | Diels-Alder ring-opening process | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2024-03-19 | — | — | US | disclosed |
| EP-3788030-B1 | DIELS- ALDER RING-OPENING PROCESS | TNO (NL) | 2023-06-07 | — | — | EP | disclosed |
| US-20210115005-A1 | DIELS-ALDER RING-OPENING PROCESS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2021-04-22 | — | — | US | disclosed |
| EP-3788030-A1 | DIELS- ALDER RING-OPENING PROCESS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2021-03-10 | — | — | EP | disclosed |
| US-20110204341-A1 | ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS | PLEXTRONICS, INC. | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115005-A1 | DIELS-ALDER RING-OPENING PROCESS | SQLE, GFER, OXER1 | MAPK1 1636/4885CYP1B1 63/4885ALDH1A1 38/4885 |
| US-11932616-B2 | Diels-Alder ring-opening process | SQLE, GFER, OXER1 | MAPK1 1636/4885CYP1B1 63/4885ALDH1A1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.