Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25819734 | 0.84 | POLB (0.34) | KDM4ELMNAPOLBALDH1A1 | |
| SCHEMBL15281169 | 0.83 | MTNR1A (0.35) | TSHRF2RL1TP53 | |
| SCHEMBL19237476 | 0.83 | CA12 (0.34) | KDM4ECYP2C19F2RL1 | |
| SCHEMBL15281105 | 0.78 | RAB9A (0.32) | HPGDKDM4ELMNAALDH1A1F2RL1 | |
| SCHEMBL25819729 | 0.78 | KMT2A (0.33) | KDM4ELMNAPOLBALDH1A1TSHR | |
| SCHEMBL25819728 | 0.77 | DPP4 (0.35) | POLBALDH1A1MAPT | |
| SCHEMBL18761189 | 0.76 | HDAC3 (0.35) | POLB | |
| SCHEMBL15281111 | 0.76 | CHRNA7 (0.38) | KDM4EALDH1A1MAPT | |
| SCHEMBL17586038 | 0.76 | CHRNA7 (0.38) | KDM4EALDH1A1MAPT | |
| SCHEMBL15223677 | 0.76 | CHRNA7 (0.38) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999083-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2011-08-16 | — | — | US | disclosed |