Betazole

Betazole

SCHEMBL1237745

Cl.NCCc1ccn[nH]1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

HRH2

The experimentally established mechanism targets of Betazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betazole SCHEMBL29633745 1.00 HRH2 (0.95)
Betazole SCHEMBL3336050 0.98 HRH2 (1.00)
Betazole SCHEMBL157156 0.98
Betazole SCHEMBL1649674 0.95 HRH2 (0.95)
SCHEMBL4711257 0.84
Betazole SCHEMBL3336046 0.80 USP2 (0.68)
SCHEMBL2183872 0.78
SCHEMBL21721708 0.74
SCHEMBL4222977 0.74
Bromide SCHEMBL10400923 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133679-A1 COMPOUNDS AND COMPOSITION FOR DNA PROTECTION ASSOCIAÇÃO PARA DESENVOLVIMENTO DO CENTRO ACADÉMICO DE INVESTIGAÇÃO E FORMAÇÃO BIOMÉDICA DO ALGARVE, AD-ABC (PT) 2025-06-26 WO claimed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 US disclosed
WO-2025133679-A1 COMPOUNDS AND COMPOSITION FOR DNA PROTECTION ASSOCIAÇÃO PARA DESENVOLVIMENTO DO CENTRO ACADÉMICO DE INVESTIGAÇÃO E FORMAÇÃO BIOMÉDICA DO ALGARVE, AD-ABC (PT) 2025-06-26 WO disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
WO-2023187599-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES DIDENKO KIRILL (MX) 2023-10-05 WO disclosed
US-11246873-B2 Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate THE SCRIPPS RESEARCH INSTITUTE (US) 2022-02-15 US disclosed
US-20210330611-A1 THERAPY FOR NEUROLOGICAL DISEASES/DISORDERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-10-28 US disclosed
US-20210290771-A1 ENGINEERED RECEPTOR/LIGAND SYSTEM FOR DELIVERY OF THERAPEUTIC AGENTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-09-23 US disclosed
US-11000597-B2 Engineered receptor/ligand system for delivery of therapeutic agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-05-11 US disclosed
US-20080319092-A1 Transdermal Drug Delivery Formulation NUVO RESEARCH INC. (CA) 2008-12-25 US disclosed
EP-1909772-A1 TRANSDERMAL DRUG DELIVERY FORMULATION Nuvo Research Inc. (CA) 2008-04-16 EP disclosed
US-20070269379-A1 Penetration Enhancer Combinations for Transdermal Delivery REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2007-11-22 US disclosed
WO-2007016766-A1 TRANSDERMAL DRUG DELIVERY FORMULATION NUVO RESEARCH INC. (CA) 2007-02-15 WO disclosed
WO-2005009510-A2 PENETRATION ENHANCER COMBINATIONS FOR TRANSDERMAL DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-03 WO disclosed
EP-1223919-A1 SWELLABLE DELIVERY SYSTEM Universiteit Leiden (NL) 2002-07-24 EP disclosed
WO-2001030322-A1 SWELLABLE DELIVERY SYSTEM UNIVERSITEIT LEIDEN (NL) 2001-05-03 WO disclosed
EP-1095650-A1 Double phase time-controlled release system Universiteit Leiden (NL) 2001-05-02 EP disclosed
US-4349674-A Quinoalinyl esters of carbamimidothioic acids AMERICAN HOME PRODUCTS CORPORATION (US) 1982-09-14 US disclosed
US-4056609-A Article for diagnosis of achlorhydria GUNN, KIRCHUBEL & MILLER (US) 1977-11-01 US disclosed