SCHEMBL123775

SCHEMBL123775

CC(C)c1ccccc1Oc1ccc(Oc2ccccc2C(C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.58
HTR2A P28223 4/20 0.58
AR P10275 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
P2RX3 P56373 1/20 0.49
P2RX2 Q9UBL9 1/20 0.49
KCNH2 Q12809 2/20 0.47
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
MEN1 O00255 1/20 0.44
CYP3A4 P08684 1/20 0.44
RECQL P46063 1/20 0.44
KMT2A Q03164 1/20 0.44
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
SLC6A2 P23975 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682183 0.93 SLC6A4 (0.51) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL18878420 0.92 SLC6A4 (0.51) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL13160049 0.92 SLC6A4 (0.54) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL5609460 0.92 ALDH1A1 (0.55) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL6437015 0.92 SLC6A4 (0.70) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL7950202 0.90 NCOA1 (0.51) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL5609057 0.90 HTR2A (0.71) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL6061211 0.90 HTR2A (0.50) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL4575432 0.88 P2RX3 (0.58) SLC6A4HTR2AARL3MBTL1ALDH1A1
SCHEMBL29959656 0.88 P2RX3 (0.58) SLC6A4HTR2AARL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2170 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084226-B1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-02-27 EP claimed
US-8114952-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-02-14 US claimed
US-8106126-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-31 US claimed
EP-2288661-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-03-02 EP claimed
EP-2285903-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-02-23 EP claimed
US-7655737-B2 Blend of polycarbonate comprising 10-90 mole percent acrylate units and polyester; improved toughness, impact strength; improvements retained after heat aging or at low temperatures, and obtained without having detrimental effect on other desirable properties such as transparency SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-02 US claimed
WO-2009140611-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-19 WO claimed
US-20090286062-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
WO-2009140610-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-19 WO claimed
US-20090286921-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
EP-2084226-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-08-05 EP claimed
EP-2081992-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE Sabic Innovative Plastics IP B.V. (NL) 2009-07-29 EP claimed
WO-2008063722-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO claimed
WO-2008060726-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-22 WO claimed
US-20080119618-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
US-20080119617-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
EP-4247890-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECH BV (NL) 2026-05-13 EP disclosed
US-6423813-B1 FROM PHENOLIC COMPOUNDS TEIJIN LIMITED (JP) 2002-07-23 US disclosed
EP-1179556-A1 BRANCHED AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND BLOW-MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-02-13 EP disclosed