Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17187694 | 0.91 | MEN1 (0.38) | MEN1KMT2AMAPK1TSHRNPC1 | |
| SCHEMBL19220498 | 0.86 | MAPK1 (0.41) | MEN1KMT2AMAPK1TSHRNPC1 | |
| SCHEMBL17199107 | 0.85 | HDAC3 (0.48) | MEN1KMT2AMAPK1TSHRNPC1 | |
| SCHEMBL29473405 | 0.84 | POLB (0.52) | POLBL3MBTL1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL17187688 | 0.84 | POLB (0.52) | POLBL3MBTL1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL17187715 | 0.83 | KMT2A (0.44) | MEN1KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL17199290 | 0.82 | HTT (0.43) | MEN1KMT2AMAPK1TSHRNPC1 | |
| SCHEMBL17199293 | 0.82 | CYP1A2 (0.54) | POLBALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL17199220 | 0.78 | GLO1 (0.47) | MEN1KMT2ATSHRNPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL17187687 | 0.77 | POLB (0.45) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131882-A1 | PHENAZINIUM MEDIATORS | Roche Diagnostics GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015158645-A1 | PHENAZINIUM MEDIATORS | ROCHE DIAGNOSTICS GMBH (DE) | 2015-10-22 | — | — | WO | disclosed |
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |