Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22203993 | 0.92 | HTT (0.38) | HTTMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17199107 | 0.92 | HDAC3 (0.48) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19220498 | 0.86 | MAPK1 (0.41) | HTTMAPTCYP1A2CYP2C19HDAC3 | |
| SCHEMBL29473405 | 0.86 | POLB (0.52) | HTTCYP1A2CYP2C19HDAC3HDAC4 | |
| SCHEMBL17187688 | 0.86 | POLB (0.52) | HTTCYP1A2CYP2C19HDAC3HDAC4 | |
| SCHEMBL17199212 | 0.85 | HTT (0.55) | HTTMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17199293 | 0.84 | CYP1A2 (0.54) | MAPTCYP1A2CYP2C19ALDH1A1GAA | |
| SCHEMBL12377714 | 0.82 | MEN1 (0.43) | HTTMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17199320 | 0.81 | HDAC3 (0.56) | HTTMAPTCYP1A2CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL17187687 | 0.79 | POLB (0.45) | HTTMAPTCYP1A2CYP2C19HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131882-B1 | PHENAZINIUM MEDIATORS | ROCHE DIAGNOSTICS GMBH (DE) | 2020-07-15 | — | — | EP | disclosed |
| US-9988358-B2 | Phenazinium mediators | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170226068-A1 | PHENAZINIUM MEDIATORS | ROCHE DIAGNOSTICS GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| WO-2015158645-A1 | PHENAZINIUM MEDIATORS | ROCHE DIAGNOSTICS GMBH (DE) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226068-A1 | PHENAZINIUM MEDIATORS | IL5, TRPV5, TRPM5 | HTT 1007/4885MAPT 577/4885CYP1A2 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.