⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12778331 | 0.69 | L3MBTL1 (0.39) | — | |
| SCHEMBL12344272 | 0.69 | — | — | |
| SCHEMBL12561756 | 0.56 | — | — | |
| SCHEMBL19086920 | 0.53 | — | — | |
| SCHEMBL12149799 | 0.53 | TDP2 (0.36) | — | |
| SCHEMBL12631892 | 0.53 | CDK8 (0.40) | — | |
| SCHEMBL14981440 | 0.53 | ADORA2A (0.40) | — | |
| SCHEMBL14907242 | 0.53 | — | — | |
| SCHEMBL12377771 | 0.53 | — | — | |
| SCHEMBL2206771 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221841-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150191490-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20140018399-A1 | MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8580828-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130109656-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. | 2013-05-02 | — | — | US | disclosed |
| US-7998954-B2 | Pyrimidodiazepinone derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20100197696-A1 | PESTICIDAL HETEROCYCLIC DIHALOALLYL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100197696-A1 | PESTICIDAL HETEROCYCLIC DIHALOALLYL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100190775-A1 | PYRIMIDODIAZEPINONE DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD (JP) | 2010-07-29 | — | — | US | disclosed |
| US-7723362-B2 | Pesticidal heterocyclic dihaloallyl compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723362-B2 | Pesticidal heterocyclic dihaloallyl compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20070299064-A1 | Pesticidal Heterocyclic Dihaloallyl Compounds | SYNGENTA CROP PROTECTION, INC. | 2007-12-27 | — | — | US | disclosed |
| US-20070299064-A1 | Pesticidal Heterocyclic Dihaloallyl Compounds | SYNGENTA CROP PROTECTION, INC. | 2007-12-27 | — | — | US | disclosed |