Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 7/20 | 0.41 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18781806 | 0.86 | NPSR1 (0.44) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL14132692 | 0.86 | TARBP2 (0.44) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL17162432 | 0.84 | NPSR1 (0.45) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL14132996 | 0.84 | NPSR1 (0.48) | NPSR1TARBP2ALDH1A1FBP1L3MBTL1 | |
| SCHEMBL28352773 | 0.83 | NPSR1 (0.44) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL18781801 | 0.81 | NPSR1 (0.42) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL17725618 | 0.81 | NPSR1 (0.39) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL9917050 | 0.79 | HCAR2 (0.39) | TARBP2PDCD4FBP1KDM4EHCRTR1 | |
| SCHEMBL9917051 | 0.78 | HCRTR1 (0.48) | NPSR1TARBP2PDCD4ALDH1A1FBP1 | |
| SCHEMBL17725616 | 0.78 | NPSR1 (0.39) | NPSR1TARBP2PDCD4ALDH1A1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311835-A1 | NOVEL ANTIBIOTICS | NOVOBIOTIC PHARMACEUTICALS LLC (US) | 2016-10-27 | — | — | US | disclosed |
| US-20120302613-A1 | NOVEL ANTIBIOTICS | NOVOBIOTIC PHARMACEUTICALS LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-7998954-B2 | Pyrimidodiazepinone derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302613-A1 | NOVEL ANTIBIOTICS | NRDC, TREH, MRPL21 | NPSR1 3592/4885TARBP2 3526/4885PDCD4 2589/4885 |
| US-20160311835-A1 | NOVEL ANTIBIOTICS | NRDC, TREH, MRPL21 | NPSR1 3592/4885TARBP2 3526/4885PDCD4 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.