Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 6/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18781940 | 0.85 | HCRTR1 (0.39) | HCAR2TARBP2HCRTR1HCRTR2GRIA1 | |
| SCHEMBL348144 | 0.82 | HCRTR1 (0.35) | HCAR2TARBP2HCRTR1HCRTR2GRIA1 | |
| SCHEMBL17162356 | 0.82 | HCRTR1 (0.35) | HCAR2TARBP2HCRTR1HCRTR2GRIA1 | |
| SCHEMBL2839466 | 0.82 | HCAR2 (0.41) | HCAR2TARBP2HCRTR1HCRTR2FBP1 | |
| SCHEMBL2570229 | 0.82 | GAA (0.38) | HCAR2GAATARBP2FBP1NPC1 | |
| SCHEMBL18781937 | 0.79 | HCRTR1 (0.38) | TARBP2HCRTR1HCRTR2GRIA1GRIA3 | |
| SCHEMBL12377784 | 0.79 | NPSR1 (0.47) | GAATARBP2HCRTR1HCRTR2PDCD4 | |
| SCHEMBL9917051 | 0.75 | HCRTR1 (0.48) | GAATARBP2HCRTR1HCRTR2PDCD4 | |
| SCHEMBL2592346 | 0.74 | FBP1 (0.38) | HCAR2GAAFBP1 | |
| SCHEMBL287238 | 0.74 | ALDH1A1 (0.33) | HCAR2TARBP2GRIA1GRIA3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149710-A1 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149710-A1 | SORTASE A INHIBITORS | STS, ENGASE, SPR | HCAR2 1820/4885GAA 34/4885TARBP2 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.