Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378352 | 0.91 | CSNK1D (0.33) | BCL2L1LIPG | |
| SCHEMBL12378698 | 0.91 | KIT (0.30) | KIT | |
| SCHEMBL12378712 | 0.90 | LIPG (0.34) | BCL2L1LIPGALDH1A1NPC1LMNA | |
| SCHEMBL12378702 | 0.90 | TACR1 (0.33) | BCL2L1LIPG | |
| SCHEMBL12378696 | 0.90 | — | — | |
| SCHEMBL12378695 | 0.88 | — | — | |
| SCHEMBL12378714 | 0.88 | LIPG (0.35) | LIPGALDH1A1NPC1LMNAMAPT | |
| SCHEMBL12378717 | 0.88 | PREP (0.33) | LIPGALDH1A1KITNPC1MAPT | |
| SCHEMBL12378723 | 0.87 | MEN1 (0.35) | ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL12378703 | 0.87 | LIPG (0.36) | LIPGALDH1A1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008287-B2 | Use treating HIV and AIDS; tricyclic compounds such as those based on 5-sulfonamido-9-hydroxy-6,8-dihydrdo-7H-pyrrolo[3,4-g]quinoline-8-one | GILEAD SCIENCES, INC. (US) | 2011-08-30 | — | — | US | disclosed |