Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL4211335 | 0.83 | CYP2D6 (0.61) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8867741 | 0.81 | CYP2D6 (0.62) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8867724 | 0.81 | CYP2D6 (0.62) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| Toluene SCHEMBL180606 | 0.79 | SMN1; SMN2 (0.65) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13836876 | 0.79 | SMN1; SMN2 (0.73) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL932442 | 0.79 | SMN1; SMN2 (0.73) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| Benzene SCHEMBL5085625 | 0.79 | SMN1; SMN2 (0.64) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL12378742 | 0.78 | LMNA (0.41) | CYP2D6SMN1; SMN2TSHRLMNAKDM4E | |
| P-Xylene SCHEMBL1904190 | 0.78 | BCHE (0.54) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 | |
| Mandelic Acid SCHEMBL16499233 | 0.78 | LMNA (0.60) | CYP2D6MAPK1SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943200-B1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-7994372-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7462750-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | CDC73, PARN, PFAS | CYP2D6 186/4885MAPK1 1894/4885SMN1; SMN2 3821/4885 |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | CDC73, PARN, PFAS | CYP2D6 201/4885MAPK1 2028/4885SMN1; SMN2 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.