Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | MGAM | O43451 | 4/20 | 0.54 |
| ▸ | SI | P14410 | 3/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | XDH | P47989 | 5/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12636901 | 0.86 | MGAM (0.51) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL3780427 | 0.75 | ALDH1A1 (0.53) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL24437990 | 0.74 | MAPT (0.50) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL3784810 | 0.74 | ALDH1A1 (0.54) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL22738241 | 0.73 | MEN1 (0.78) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL14384481 | 0.72 | GAA (0.48) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL24959580 | 0.72 | GAA (0.48) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL9838561 | 0.72 | MGAM (1.00) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL30542658 | 0.72 | MGAM (1.00) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL18598171 | 0.71 | ALDH1A1 (0.36) | GAAMGAMSIMGAM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190514-A1 | PYRONE ANALOG COMPOSITIONS AND METHODS | LIMERICK BIOPHARMA, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190514-A1 | PYRONE ANALOG COMPOSITIONS AND METHODS | CYP11B2, CYP11B1, GLS2 | GAA 2277/4885MGAM 3993/4885SI 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.