SCHEMBL12379514

SCHEMBL12379514

Cc1ccc(-c2ccc3c(-c4ccccc4)c4cc(-c5ccc(N(C)c6cccc(CCCc7ccc8c(c7)CC8)c6)cc5)ccc4c(-c4ccccc4)c3c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHKA P35790 6/20 0.34
CHKB Q9Y259 1/20 0.31
FFAR1 O14842 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12379488 0.89 SIGMAR1 (0.33) CHKA
SCHEMBL12619690 0.87 CHKA (0.35) CHKAFFAR1
SCHEMBL12379486 0.85 SIGMAR1 (0.35) CHKA
SCHEMBL12379497 0.85 SIGMAR1 (0.35) CHKA
SCHEMBL12619714 0.85 SIGMAR1 (0.35) CHKA
SCHEMBL12379527 0.84 SIGMAR1 (0.36) CHKA
SCHEMBL12379519 0.83 CHKA (0.37) CHKAFFAR1
SCHEMBL12379524 0.83 MTNR1A (0.34) CHKA
SCHEMBL12379556 0.82 CHKA (0.41) CHKACHKB
SCHEMBL12379528 0.81 SIGMAR1 (0.37) CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110198573-A1 CHARGE-TRANSPORTING POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-18 US disclosed