SCHEMBL12379561

SCHEMBL12379561

CCCCCCc1ccc(N(C)c2ccc(-c3ccc4c(ccc5cc(-c6ccc(C)cc6)ccc54)c3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.44
HSD17B10 Q99714 3/20 0.42
TSHR P16473 1/20 0.42
RARA P10276 2/20 0.41
RARG P13631 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
MTOR P42345 1/20 0.41
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
ATM Q13315 1/20 0.39
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12379553 0.88 HSD17B10 (0.51) RARBHSD17B10TSHRRARARARG
SCHEMBL12619459 0.88 HSD17B10 (0.51) RARBHSD17B10TSHRRARARARG
SCHEMBL12619649 0.85 HSD17B10 (0.49) RARBHSD17B10TSHRRARAALDH1A1
SCHEMBL19422233 0.85 HSD17B10 (0.49) RARBHSD17B10TSHRRARAALDH1A1
SCHEMBL12379502 0.85 IGF1R (0.35) RARBMEN1KMT2ALMNAHRH3
SCHEMBL12588009 0.81 LPL (0.49) HSD17B10ALDH1A1ESR1ADRA2AADORA3
SCHEMBL12619749 0.81 HSD11B1 (0.51) RARBHSD17B10TSHRRARARARG
SCHEMBL12379589 0.81 HSD17B10 (0.44) RARBHSD17B10TSHRRARAALDH1A1
SCHEMBL12619731 0.81 HSD11B1 (0.48) RARBHSD17B10TSHRRARARARG
SCHEMBL12262920 0.80 RARB (0.45) RARBHSD17B10TSHRRARAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110198573-A1 CHARGE-TRANSPORTING POLYMER, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC EL DISPLAY, AND ORGANIC EL LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-18 US disclosed