SCHEMBL12379814

SCHEMBL12379814

C=CCOc1ccc(C(=O)Oc2ccc(-c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
KMT2A Q03164 4/20 0.51
GFER P55789 1/20 0.51
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
PRSS1 P07477 1/20 0.48
ACR P10323 1/20 0.48
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47
NPC1 O15118 2/20 0.47
POLB P06746 2/20 0.47
RAB9A P51151 2/20 0.47
PKM P14618 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10580680 1.00 MAPT (0.51) MAPTKMT2AGFERLMNASMN1; SMN2
SCHEMBL10580996 1.00 MAPT (0.51) MAPTKMT2AGFERLMNASMN1; SMN2
SCHEMBL10580343 1.00 MAPT (0.51) MAPTKMT2AGFERLMNASMN1; SMN2
SCHEMBL7776960 0.96 MAPT (0.55) MAPTKMT2AGFERLMNASMN1; SMN2
SCHEMBL5089928 0.96 MAPT (0.55) MAPTKMT2AGFERLMNASMN1; SMN2
SCHEMBL7868900 0.96 MAPT (0.55) MAPTKMT2AGFERLMNASMN1; SMN2
SCHEMBL8026374 0.88 NPC1 (0.52) MAPTKMT2ASMN1; SMN2PRSS1ACR
SCHEMBL7619158 0.88 NPC1 (0.52) MAPTKMT2ASMN1; SMN2PRSS1ACR
SCHEMBL8825667 0.87 BACE1 (0.52) MAPTKMT2ALMNASMN1; SMN2ADRB2
SCHEMBL10332262 0.86 MAPT (0.47) MAPTKMT2ASMN1; SMN2ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9093643-B2 Deformable material and actuator SEIKO EPSON CORPORATION (JP) 2015-07-28 US disclosed
US-8436117-B2 Stimuli responsive compound, stimuli responsive compound polymer, actuator and method for manufacturing stimuli responsive compound SEIKO EPSON CORPORATION (JP) 2013-05-07 US disclosed
US-20110196120-A1 STIMULI RESPONSIVE COMPOUND, STIMULI RESPONSIVE COMPOUND POLYMER, ACTUATOR AND METHOD FOR MANUFACTURING STIMULI RESPONSIVE COMPOUND SEIKO EPSON CORPORATION (JP) 2011-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196120-A1 STIMULI RESPONSIVE COMPOUND, STIMULI RESPONSIVE COMPOUND POLYMER, ACTUATOR AND METHOD FOR MANUFACTURING STIMULI RESPONSIVE COMPOUND PUF60, RPSA, RPS16 MAPT 1802/4885KMT2A 4409/4885GFER 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.