SCHEMBL1237982

SCHEMBL1237982

CCC(CO)COC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
LMNA P02545 2/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 3/20 0.40
CYP3A4 P08684 3/20 0.40
ATM Q13315 1/20 0.40
PRKCA P17252 3/20 0.36
RECQL P46063 2/20 0.35
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA2 P00918 1/20 0.35
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12905144 1.00 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL12905143 1.00 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL5358516 0.88 TDP1 (0.45) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL13459987 0.88 TDP1 (0.45) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL27305 0.88 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL12889164 0.88 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL11750627 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL6903483 0.83 ALDH1A1 (0.62) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL14571350 0.83 CYP3A4 (0.40) ALDH1A1LMNAHSD17B10TDP1TSHR
SCHEMBL7185162 0.83 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888105-B2 N-acetyl-dl-phenylalanine propyl ester; meso cis-4-cyclopentene-1,3-diol; N-trifluoroacetyl-dl-phenylalanine propyl ester INEOUS FLUOR HOLDINGS LIMITED (GB) 2011-02-15 US disclosed
EP-1604030-B1 ENZYMATIC PROCESS FOR STEREO-SELECTIVE PREPARATION OF CHEMICAL COMPOUNDS IN HYDROFLUOROCARBON SOLVENTS INEOS FLUOR HOLDINGS LTD (GB) 2007-06-20 EP disclosed
US-20070128705-A1 Enzymatic process for stereo-selective preparation of chemical compounds in hydrofluorocarbon solvents INEOS FLUOR HOLDINGS LIMITED, C/O INEOS LIMITED (GB) 2007-06-07 US disclosed
EP-1604030-A1 ENZYMATIC PROCESS FOR STEREO-SELECTIVE PREPARATION OF CHEMICAL COMPOUNDS IN HYDROFLUOROCARBON SOLVENTS Ineos Fluor Holdings Limited (GB) 2005-12-14 EP disclosed
WO-2004083444-A1 ENZYMATIC PROCESS FOR STEREO-SELECTIVE PREPARATION OF CHEMICAL COMPOUNDS IN HYDROFLUOROCARBON SOLVENTS INEOS FLUOR HOLDINGS LIMITED (GB) 2004-09-30 WO disclosed