Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890916 | 0.93 | CTSL (0.68) | CTSLKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10893970 | 0.92 | CTSL (0.67) | CTSLKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10063754 | 0.91 | CTSL (0.71) | CTSLKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL20204704 | 0.91 | CTSL (0.72) | CTSLKDM4EMEN1KMT2AHCRTR1 | |
| SCHEMBL20204701 | 0.91 | CTSL (0.72) | CTSLKDM4EMEN1KMT2AHCRTR1 | |
| SCHEMBL18232014 | 0.87 | CTSL (0.65) | CTSLKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL26334901 | 0.87 | CTSL (0.65) | CTSLKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10077743 | 0.86 | CTSL (0.62) | CTSLKDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL13254023 | 0.86 | CTSL (0.71) | CTSLKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7123258 | 0.86 | CTSL (0.71) | CTSLKDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994119-B2 | Neuropeptide Y receptor antagonists and agonists including O-glycosylated tripeptides, O-glycopeptides, and extended tripeptides; cardiovascular disorders | UNIVERSITY OF CINCINNATI (US) | 2011-08-09 | — | — | US | disclosed |