SCHEMBL12386238

SCHEMBL12386238

C/N=C1\NC(=O)c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 1/20 0.58
▸ CASP3 P42574 2/20 0.50
▸ CASP7 P55210 2/20 0.50
▸ CASP6 P55212 2/20 0.50
▸ CASP8 Q14790 2/20 0.50
▸ CASP2 P42575 1/20 0.50
▸ PARP1 P09874 3/20 0.43
▸ ACVR1 Q04771 2/20 0.43
▸ LRRK2 Q5S007 2/20 0.43
▸ PDGFRA P16234 1/20 0.43
▸ FER P16591 1/20 0.43
▸ LTK P29376 1/20 0.43
▸ CDK8 P49336 1/20 0.43
▸ DYRK1B Q9Y463 1/20 0.43
▸ SMN1; SMN2 Q16637 5/20 0.41
▸ LMNA P02545 2/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ CDC25B P30305 2/20 0.40
▸ MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11241184 0.78 GSK3B (0.58) GSK3BCASP3CASP7CASP6CASP8
SCHEMBL11241188 0.78 GSK3B (0.58) GSK3BCASP3CASP7CASP6CASP8
SCHEMBL28050567 0.78 GSK3B (0.52) GSK3BCASP3CASP7CASP6CASP8
SCHEMBL2617090 0.77 GSK3B (0.56) GSK3BCASP3CASP7CASP6CASP8
SCHEMBL13995656 0.77 GSK3B (0.56) GSK3BCASP3CASP7CASP6CASP8
SCHEMBL12386245 0.77 GSK3B (0.56) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL23063638 0.76 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29366030 0.75 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL30125197 0.75 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL64 0.75 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003712-B2 Resin composition and process for producing resin molding SONY CORPORATION (JP) 2011-08-23 — — US disclosed
US-8003712-B2 Resin composition and process for producing resin molding SONY CORPORATION (JP) 2011-08-23 — — US disclosed
EP-2256166-A1 Resin composition and process for producing resin molding Sony Corporation (JP) 2010-12-01 — — EP disclosed
US-20100144936-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING RESIN MOLDING SONY CORPORATION (JP) 2010-06-10 — — US disclosed
US-20100144936-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING RESIN MOLDING SONY CORPORATION (JP) 2010-06-10 — — US disclosed
US-7691928-B2 Resin composition and process for producing resin molding SONY CORPORATION (JP) 2010-04-06 — — US disclosed
US-7691928-B2 Resin composition and process for producing resin molding SONY CORPORATION (JP) 2010-04-06 — — US disclosed
US-7671117-B2 Resin composition SONY CORPORATION (JP) 2010-03-02 — — US disclosed
US-7671117-B2 Resin composition SONY CORPORATION (JP) 2010-03-02 — — US disclosed
US-20090005475-A1 RESIN COMPOSITION SONY CORPORATION (JP) 2009-01-01 — — US disclosed
US-20090005475-A1 RESIN COMPOSITION SONY CORPORATION (JP) 2009-01-01 — — US disclosed
EP-1990365-A1 Resin composition Sony Corporation (JP) 2008-11-12 — — EP disclosed
US-20070226919-A1 Method for Dyeing or Printing Textile Materials HUNTSMAN INTERNATIONAL LLC (US) 2007-10-04 — — US disclosed
Send feedback