Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241184 | 1.00 | GSK3B (0.58) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL11036987 | 0.84 | C3AR1 (0.41) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL12386238 | 0.78 | GSK3B (0.58) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL2617090 | 0.77 | GSK3B (0.56) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL12386245 | 0.77 | GSK3B (0.56) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL13995656 | 0.77 | GSK3B (0.56) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL1616990 | 0.76 | GSK3B (0.88) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL64 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL30125197 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL11040503 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366312-A | Metal complexes of isoindolinazines, process for their preparation and use | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |
| US-4102892-A | Process for the preparation of copper phthylocyanine | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
| US-4024132-A | Azomethine pigments | CIBA-GEIGY CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3974149-A | TONERS | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |