Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.75 |
| ▸ | DRD4 | P21917 | 3/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.75 |
| ▸ | HRH2 | P25021 | 2/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.75 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.75 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.75 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | HTR2B | P41595 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387689 | 0.94 | OPRM1 (0.72) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL12387685 | 0.92 | OPRM1 (0.78) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL12433713 | 0.88 | OPRM1 (0.78) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL2313168 | 0.86 | OPRM1 (1.00) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL12387673 | 0.86 | OPRM1 (1.00) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL14580936 | 0.85 | OPRM1 (1.00) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| Hydrochloric Acid SCHEMBL7170114 | 0.85 | OPRM1 (0.98) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL2310814 | 0.82 | OPRM1 (0.85) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL12387698 | 0.82 | OPRM1 (0.85) | OPRM1ADRA2ADRD4SLC6A4HRH2 | |
| SCHEMBL9105318 | 0.81 | OPRM1 (0.87) | OPRM1ADRA2ADRD4SLC6A4HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989630-B2 | Radiotracers for imaging P-glycoprotein function | NATIONAL INSTITUTES OF HEALTH REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) | 2011-08-02 | — | — | US | disclosed |
| US-20090274624-A1 | RADIOTRACERS FOR IMAGING P-GLYCOPROTEIN FUNCTION | NATIONAL INSTITUTES OF HEALTH REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274624-A1 | RADIOTRACERS FOR IMAGING P-GLYCOPROTEIN FUNCTION | ABCC1, ABCB1, SLC47A2 | OPRM1 366/4885ADRA2A 535/4885DRD4 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.