SCHEMBL2310814

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14580936	0.92	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2
	SCHEMBL12387698	0.89	OPRM1 (0.85)	OPRM1ADRA2ADRD4SLC6A4HRH2
	SCHEMBL21538258	0.87	OPRM1 (0.82)	OPRM1ADRA2ADRD4SLC6A4HRH2
	Loperamide SCHEMBL12387663	0.86	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2
	SCHEMBL12387673	0.86	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2
	Loperamide SCHEMBL28530	0.86	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2
	SCHEMBL2313168	0.86	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2
	Loperamide SCHEMBL8409779	0.86	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2
	SCHEMBL9105318	0.85	OPRM1 (0.87)	OPRM1ADRA2ADRD4SLC6A4HRH2
	Loperamide SCHEMBL8409268	0.85	OPRM1 (1.00)	OPRM1ADRA2ADRD4SLC6A4HRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.