SCHEMBL1239697

SCHEMBL1239697

C=Cc1c(S(=O)(=O)OCC)ccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
GAA P10253 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 3/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NR1I2 O75469 1/20 0.37
HPGD P15428 3/20 0.36
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ERN1 O75460 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC2A1 P11166 1/20 0.35
MAPK1 P28482 2/20 0.35
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1240303 0.79 SLC2A1 (0.36) L3MBTL1GAATDP1MAPTALDH1A1
SCHEMBL1239735 0.79 NR1I2 (0.41) L3MBTL1GAATDP1KDM4ECYP1A2
SCHEMBL2199067 0.79 CA1 (0.52) ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL314320 0.79 ALDH1A1 (0.35) GAAMAPTALDH1A1KDM4EHPGD
Formaldehyde SCHEMBL18139835 0.78 CA1 (0.47) ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL2761905 0.78 CA1 (0.50) ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL8332473 0.78 CA1 (0.50) ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL368409 0.77 ERN1 (0.44) L3MBTL1GAATDP1MAPTALDH1A1
SCHEMBL313316 0.74 ALDH1A1 (0.38) GAAALDH1A1
SCHEMBL26965297 0.73 PTPN1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7892694-B2 Electrolytic membrane, process for producing the same, membrane electrode assembly, fuel cell and method of operating the same KABUSHIKI KAISHA TOSHIBA (JP) 2011-02-22 US disclosed
US-20070166590-A1 ELECTROLYTIC MEMBRANE, PROCESS FOR PRODUCING THE SAME, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL AND METHOD OF OPERATING THE SAME KABUSHIKI KAISHA TOSHIBA (JP) 2007-07-19 US disclosed