SCHEMBL314320

SCHEMBL314320

C=Cc1ccc(S(=O)(=O)OCC)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.35
LMNA P02545 6/20 0.35
TSHR P16473 6/20 0.35
HTT P42858 4/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
HPGD P15428 5/20 0.33
MAPT P10636 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALOX12 P18054 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
NTSR1 P30989 1/20 0.33
CCR6 P51684 1/20 0.33
MCL1 Q07820 1/20 0.33
HSD17B10 Q99714 2/20 0.33
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
SMN1; SMN2 Q16637 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL327259 0.85 ALDH1A1 (0.34) ALDH1A1LMNATSHRHTTMCOLN3
SCHEMBL313915 0.83 ALDH1A1 (0.33) ALDH1A1MCL1LDHA
SCHEMBL313316 0.81 ALDH1A1 (0.38) ALDH1A1MCL1GAA
SCHEMBL1239712 0.79 MAPT (0.30) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL1239717 0.79
SCHEMBL1239697 0.79 L3MBTL1 (0.40) ALDH1A1LMNAHPGDMAPTNPSR1
SCHEMBL9152668 0.78 TTR (0.41) ALDH1A1LMNATSHRHTTMCOLN3
SCHEMBL8615019 0.77 LDHA (0.37) ALDH1A1TSHRMEN1KMT2AMCL1
SCHEMBL1240303 0.77 SLC2A1 (0.36) ALDH1A1LMNAHPGDMAPTMEN1
SCHEMBL26965297 0.76 PTPN1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093342-B2 Polymer, charge control agent, and toner for developing electrostatic latent images CANON KABUSHIKI KAISHA (JP) 2012-01-10 US disclosed
US-20100291482-A1 NOVEL POLYMER, CHARGE CONTROL AGENT, AND TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGES CANON KABUSHIKI KAISHA (JP) 2010-11-18 US disclosed
US-20070117945-A1 NOVEL POLYMER, CHARGE CONTROL AGENT, AND TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGES CANON KABUSHIKI KAISHA (JP) 2007-05-24 US disclosed