Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL37628 | 0.93 | ALDH1A1 (0.52) | ALDH1A1TSHRENPP2 | |
| Styrene SCHEMBL4116570 | 0.85 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPTSMN1; SMN2HPGD | |
| Styrene SCHEMBL9581006 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNAMAPTSMN1; SMN2 | |
| Styrene SCHEMBL677845 | 0.84 | ALDH1A1 (0.34) | ALDH1A1TSHRLMNAMAPTHPGD | |
| Styrene SCHEMBL6040787 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRMCL1LMNAMAPT | |
| SCHEMBL7159537 | 0.81 | MAOB (0.50) | ALDH1A1TSHRMCL1LMNAMAPT | |
| SCHEMBL9817383 | 0.81 | MAOB (0.50) | ALDH1A1TSHRMCL1LMNAMAPT | |
| SCHEMBL8948870 | 0.81 | MAOB (0.50) | ALDH1A1TSHRMCL1LMNAMAPT | |
| Styrene SCHEMBL1719524 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRMCL1LMNAMAPT | |
| Styrene SCHEMBL157052 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRMCL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633162-B2 | Angle protector | USG BORAL BUILDING PRODUCTS PTY LIMITED (AU) | 2020-04-28 | — | — | US | claimed |
| US-20180312319-A1 | ANGLE PROTECTOR | USG BORAL BUILDING PRODUCTS PTY LIMITED (AU) | 2018-11-01 | — | — | US | claimed |
| US-20110033637-A1 | Method and apparatus for printing on a surface | SONY CORPORATION | 2011-02-10 | — | — | US | claimed |
| US-6669859-B1 | Inverted sun visor mirror assembly | LEAR CORPORATION | 2003-12-30 | — | — | US | claimed |
| US-20200268591-A1 | LIP ENHANCEMENT DEVICE AND METHOD | JUVALIPS, LLC | 2020-08-27 | — | — | US | disclosed |
| US-10675208-B2 | Lip enhancement device and method | JUVALIPS, LLC (US) | 2020-06-09 | — | — | US | disclosed |
| US-10633162-B2 | Angle protector | USG BORAL BUILDING PRODUCTS PTY LIMITED (AU) | 2020-04-28 | — | — | US | disclosed |
| US-10342728-B2 | Lip enhancement device and method | JUVALIPS, LLC (US) | 2019-07-09 | — | — | US | disclosed |
| US-20190021940-A1 | LIP ENHANCEMENT DEVICE AND METHOD | JUVALIPS, LLC | 2019-01-24 | — | — | US | disclosed |
| US-20180312319-A1 | ANGLE PROTECTOR | USG BORAL BUILDING PRODUCTS PTY LIMITED (AU) | 2018-11-01 | — | — | US | disclosed |
| US-20180185235-A1 | LIP ENHANCEMENT DEVICE AND METHOD | JUVALIPS, LLC | 2018-07-05 | — | — | US | disclosed |
| CN-104737368-B | structure and wireless communication device | 夏普株式会社 | 2017-12-19 | — | — | CN | disclosed |
| CN-105265027-A | Structure, wireless communication device, and method for manufacturing structure | SHARP KK | 2016-01-20 | — | — | CN | disclosed |
| CN-105026144-A | Structural body and wireless communication device | SHARP KK | 2015-11-04 | — | — | CN | disclosed |
| CN-103282213-B | Decorative article | 3M INNOVATIVE PROPERTIES CO. (US) | 2015-08-19 | — | — | CN | disclosed |
| CN-104737368-A | structure and wireless communication device | SHARP KK | 2015-06-24 | — | — | CN | disclosed |
| CN-104704677-A | Structure and radio communication device | SHARP KK | 2015-06-10 | — | — | CN | disclosed |
| US-20110033637-A1 | Method and apparatus for printing on a surface | SONY CORPORATION | 2011-02-10 | — | — | US | disclosed |
| US-6669859-B1 | Inverted sun visor mirror assembly | LEAR CORPORATION | 2003-12-30 | — | — | US | disclosed |
| US-6007473-A | Centrifuge with reduced noise generation | KENDRO LABORATORY PRODUCTS GMBH (DE) | 1999-12-28 | — | — | US | disclosed |