Styrene

Styrene

SCHEMBL677845

C=C(CCC)C(=O)O.C=CC=CC=CC#N.C=Cc1ccccc1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4116570 0.91 ALDH1A1 (0.35) ALDH1A1TSHRMEN1MAPTHPGD
Styrene SCHEMBL7043418 0.86 ALDH1A1 (0.39) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL8332408 0.86 ALDH1A1 (0.41) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL1240151 0.84 ALDH1A1 (0.45) ALDH1A1TSHRLMNAMAPTHPGD
Styrene SCHEMBL9879339 0.83 ALDH1A1 (0.47) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL1628104 0.83 ALDH1A1 (0.50) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL37628 0.81 ALDH1A1 (0.52) ALDH1A1TSHRTDP1
SCHEMBL9067801 0.79 HDAC3 (0.40) TSHRLMNATDP1CES2CES1
SCHEMBL182733 0.79 HDAC3 (0.40) TSHRLMNATDP1CES2CES1
SCHEMBL10431824 0.79 PAM (0.44) ALDH1A1LMNATDP1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110281128-A1 Thermoplastic Product and Method for the Production of a Composite Product GOERICH GERALD (US) 2011-11-17 US disclosed