Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12412463 | 0.87 | KDM4E (0.45) | MEN1FAAHMAPK1KMT2APTGS1 | |
| SCHEMBL24358293 | 0.86 | POLB (0.41) | FAAHMAPK1PTGS1PTGS2HSD17B10 | |
| SCHEMBL17721377 | 0.84 | PTGS1 (0.58) | MEN1FAAHMAPK1KMT2APTGS1 | |
| SCHEMBL18995821 | 0.84 | PTGS1 (0.51) | FAAHMAPK1PTGS1PTGS2HPGD | |
| SCHEMBL12659454 | 0.83 | NAMPT (0.47) | FAAHMAPK1PTGS1PTGS2NAMPT | |
| SCHEMBL20752853 | 0.83 | PTGS1 (0.46) | FAAHMAPK1PTGS1PTGS2NAMPT | |
| SCHEMBL21388417 | 0.83 | PTGS1 (0.46) | FAAHMAPK1PTGS1PTGS2NAMPT | |
| SCHEMBL17175252 | 0.83 | NAMPT (0.43) | FAAHPTGS1PTGS2HSD17B10POLB | |
| SCHEMBL253991 | 0.83 | PTGS1 (0.51) | MEN1FAAHKMT2APTGS1PTGS2 | |
| SCHEMBL14984835 | 0.82 | PTGS1 (0.49) | FAAHMAPK1PTGS1PTGS2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184293-A1 | DEVICE, METHOD AND KIT FOR IN VIVO DETECTION OF A BIOMARKER | GIVEN IMAGING LTD. (IL) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184293-A1 | DEVICE, METHOD AND KIT FOR IN VIVO DETECTION OF A BIOMARKER | SERPINA3, SERPINA2, SERPINE1 | MEN1 715/4885FAAH 873/4885MAPK1 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.