Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16724823 | 0.89 | KDM4E (0.40) | KDM4EPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL12401794 | 0.87 | MEN1 (0.43) | KDM4EPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL17721377 | 0.87 | PTGS1 (0.58) | KDM4EPTGS1PTGS2MEN1KMT2A | |
| SCHEMBL23506482 | 0.86 | PTGS1 (0.41) | PTGS1PTGS2MAPTFAAHMGLL | |
| SCHEMBL24722846 | 0.85 | KDM4E (0.48) | KDM4EPTGS1PTGS2KMT2AMAPT | |
| SCHEMBL14865037 | 0.85 | CNR2 (0.41) | PTGS1PTGS2MAPTFAAHMGLL | |
| SCHEMBL24722840 | 0.85 | KDM4E (0.48) | KDM4EPTGS1PTGS2KMT2AMAPT | |
| SCHEMBL12508170 | 0.85 | PTGS1 (0.40) | KDM4EPTGS1PTGS2MAPTFAAH | |
| SCHEMBL22538847 | 0.83 | PTGS1 (0.39) | KDM4EPTGS1PTGS2MAPTFAAH | |
| SCHEMBL12107736 | 0.83 | PTGS1 (0.39) | KDM4EPTGS1PTGS2MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287030-A1 | Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions | THE GENERAL HOSPITAL CORPORATION | 2023-09-14 | — | — | US | disclosed |
| US-20220409697-A1 | Extended Half-life G-CSF and GM-CSF Vitamin D Conjugates | RAMEA LLC (US) | 2022-12-29 | — | — | US | disclosed |
| EP-3949969-A2 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | Silverback Therapeutics, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-3760639-A1 | ZWITTERIONIC POLYMER CONJUGATES | Kodiak Sciences Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20170246313-A1 | AN IMPROVED PROCESS OF CONJUGATION AND NOVEL SYNTHETIC OLIGOSACCHARIDE- PROTEIN CONJUGATES OBTAINED THEREOF | MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT. LTD. (IN) | 2017-08-31 | — | — | US | disclosed |
| WO-2017095805-A1 | ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2017-06-08 | — | — | WO | disclosed |
| US-20170145112-A1 | ANTI-FACTOR D ANTIBODIES AND CONJUGATES | GENENTECH, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9650363-B2 | Integrin antagonist conjugates for targeted delivery to cells expressing LFA-1 | HOFFMANN-LA ROCHE INC. (US) | 2017-05-16 | — | — | US | disclosed |
| US-9586916-B2 | Integrin antagonist conjugates for targeted delivery to cells expressing alpha-V-beta-3 | HOFFMANN-LA ROCHE INC. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | SQUIBB & SONS LLC (US) | 2017-03-02 | — | — | US | disclosed |
| US-9116128-B2 | Click chemistry surface functionalization for resonant micro-cavity sensors | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE (INSERM) (FR) | 2015-05-21 | — | — | US | disclosed |
| US-20110171164-A1 | POLYMER CONJUGATES OF GLP-2-LIKE PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150139901-A1 | Radioactive Rhodium Complexes, Preparation Methods and Uses Thereof | RAB35, MRPL21, MRPS35 | KDM4E 3684/4885PTGS1 4878/4885PTGS2 4875/4885 |
| US-20110165112-A1 | POLYMER CONJUGATES OF C-PEPTIDES | IAPP, GCG, INSR | KDM4E 4796/4885PTGS1 4217/4885PTGS2 4578/4885 |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | CD2BP2, CD22, CD2 | KDM4E 3321/4885PTGS1 4481/4885PTGS2 3118/4885 |
| US-20220409697-A1 | Extended Half-life G-CSF and GM-CSF Vitamin D Conjugates | CSF3R, CYP24A1, GC | KDM4E 2698/4885PTGS1 1056/4885PTGS2 1376/4885 |
| US-20170145112-A1 | ANTI-FACTOR D ANTIBODIES AND CONJUGATES | CFD, F13B, CFH | KDM4E 2617/4885PTGS1 2141/4885PTGS2 2605/4885 |
| US-20230287030-A1 | Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions | GALNT14, NEU4, CSGALNACT1 | KDM4E 933/4885PTGS1 2107/4885PTGS2 2044/4885 |
| US-20110171164-A1 | POLYMER CONJUGATES OF GLP-2-LIKE PEPTIDES | IAPP, GLP1R, GIPR | KDM4E 3559/4885PTGS1 3371/4885PTGS2 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.