Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20864144 | 0.89 | PTGS1 (0.44) | PTGS1PTGS2OPRM1OPRD1OPRK1 | |
| SCHEMBL18995821 | 0.86 | PTGS1 (0.51) | PTGS1PTGS2MGLLFAAHTP53 | |
| SCHEMBL12401794 | 0.86 | MEN1 (0.43) | POLBHSD17B10PTGS1PTGS2OPRM1 | |
| SCHEMBL17175252 | 0.86 | NAMPT (0.43) | POLBHSD17B10PTGS1PTGS2OPRM1 | |
| SCHEMBL14984835 | 0.85 | PTGS1 (0.49) | POLBHSD17B10PTGS1PTGS2MGLL | |
| SCHEMBL14868081 | 0.84 | NAMPT (0.44) | POLBHSD17B10PTGS1PTGS2OPRM1 | |
| SCHEMBL12641968 | 0.84 | LMNA (0.43) | POLBHSD17B10PTGS1PTGS2MGLL | |
| SCHEMBL22214462 | 0.84 | PTGS1 (0.42) | POLBHSD17B10PTGS1PTGS2OPRM1 | |
| SCHEMBL14240811 | 0.84 | MGLL (0.54) | HSD17B10PTGS1PTGS2MGLLFAAH | |
| SCHEMBL12132672 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2MGLLFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263896-A1 | NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF | VITALIXIR (BEIJING) CO., LTD (CN) | 2023-08-24 | — | — | US | disclosed |
| US-20230263896-A1 | NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF | VITALIXIR (BEIJING) CO., LTD (CN) | 2023-08-24 | — | — | US | disclosed |
| US-20220127323-A1 | NOVEL POLYPEPTIDE AND THERAPEUTIC USES THEREOF | VITALIXIR (BEIJING) CO., LTD (CN) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127323-A1 | NOVEL POLYPEPTIDE AND THERAPEUTIC USES THEREOF | VIP, IAPP, LNPEP | POLB 4169/4885HSD17B10 4095/4885PTGS1 3231/4885 |
| US-20230263896-A1 | NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF | VIP, IAPP, LNPEP | POLB 4033/4885HSD17B10 3964/4885PTGS1 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.