Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167562 | 0.87 | TAAR1 (0.64) | TAAR1MAOB | |
| SCHEMBL8758138 | 0.84 | MAOB (0.50) | TAAR1MAOB | |
| SCHEMBL8607813 | 0.84 | LTA4H (0.62) | TAAR1MAOB | |
| SCHEMBL1027713 | 0.82 | TAAR1 (0.63) | TAAR1MAOB | |
| SCHEMBL4303101 | 0.82 | TAAR1 (0.57) | TAAR1MAOB | |
| SCHEMBL8610726 | 0.82 | TAAR1 (0.57) | TAAR1MAOB | |
| Hydrochloric Acid SCHEMBL6575644 | 0.82 | LTA4H (0.60) | TAAR1MAOB | |
| SCHEMBL2163896 | 0.82 | TAAR1 (0.57) | TAAR1MAOB | |
| SCHEMBL14599625 | 0.82 | TAAR1 (0.57) | TAAR1MAOB | |
| SCHEMBL10305086 | 0.80 | MAOB (0.58) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703825-B2 | Compounds, use thereof as medicaments, and method of preparation thereof | UNIVERSITE DE LORRAINE (FR) | 2014-04-22 | — | — | US | disclosed |
| US-20110184070-A1 | NOVEL COMPOUNDS, USE THEREOF AS MEDICAMENTS, AND METHOD OF PREPARATION THEREOF | UNIVERSITE HENRI POINCARE NANCY 1 (FR) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184070-A1 | NOVEL COMPOUNDS, USE THEREOF AS MEDICAMENTS, AND METHOD OF PREPARATION THEREOF | CYP11B2, NPM1, B2M | TAAR1 1619/4885MAOB 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.