SCHEMBL124019

SCHEMBL124019

c1ccc2c(c1)CNCN2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
PNMT P11086 1/20 0.43
CD44 P16070 1/20 0.43
MAOB P27338 1/20 0.43
HTR5A P47898 2/20 0.42
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
HK1 P19367 1/20 0.40
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
GALK1 P51570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411963 1.00 ALOX15 (0.50) ALOX15HSD17B10PNMTCD44MAOB
Hydrogen Sulfide SCHEMBL27951535 0.98 ALOX15 (0.48) ALOX15HSD17B10PNMTCD44MAOB
Hydrochloric Acid SCHEMBL4630968 0.98 ALOX15 (0.48) ALOX15HSD17B10PNMTCD44MAOB
SCHEMBL3757557 0.88 ALOX15 (0.41) ALOX15HSD17B10PNMTCD44MAOB
Pyridine SCHEMBL19995258 0.88 ALOX15 (0.46) ALOX15HSD17B10PNMTCD44MAOB
SCHEMBL1828551 0.79
SCHEMBL30668800 0.79
SCHEMBL2041999 0.79
SCHEMBL5474126 0.79 ALOX15 (0.48) ALOX15HSD17B10PNMTCD44MAOB
SCHEMBL379799 0.79 CD44 (0.52) ALOX15HSD17B10PNMTCD44MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3684 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250338712-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2025-10-30 US claimed
CN-116375653-B Method for synthesizing chiral tetrahydroquinazoline derivative with high enantioselectivity 常州大学 2025-02-25 CN claimed
US-12150940-B2 WASp-protecting small molecules, compositions, methods and uses thereof in the treatment of innate and acquired immune-related disorders or conditions BAR ILAN UNIVERSITY (IL) 2024-11-26 US claimed
CN-114269735-B Dihydro-or tetrahydroquinazoline compound, intermediate thereof, preparation method and application 南京创济生物医药有限公司 2024-02-23 CN claimed
CN-117229222-A Method for synthesizing quinazoline by dehydrogenation of tetrahydroquinazoline 西安石油大学 2023-12-15 CN claimed
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP claimed
CN-116375653-A Method for synthesizing chiral tetrahydroquinazoline derivative with high enantioselectivity 常州大学 2023-07-04 CN claimed
EP-3421454-B1 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-04-05 EP claimed
CN-108884044-B Piperidine derivatives 大塚制药株式会社 2023-01-31 CN claimed
US-11542273-B2 Amide compound having bet proteolysis-inducing action and medicinal application thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2023-01-03 US claimed
EP-0308438-B1 LIQUID CRYSTAL PHASE CONTAINING TOLANES MERCK PATENT GmbH (DE) 1993-09-29 EP claimed
CN-1057262-A Cydic amide derivatives EISAI CO LTD (JP) 1991-12-25 CN claimed
EP-0151446-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1990-09-19 EP claimed
EP-0152808-B1 NITROGEN CONTAINING HETEROCYCLES MERCK PATENT GmbH (DE) 1990-09-12 EP claimed
EP-0209622-B1 HYDROTERPHENYLS MERCK PATENT GmbH (DE) 1989-06-07 EP claimed
EP-0149209-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1988-03-02 EP claimed
US-4707295-A LIQUID CRYSTALS, DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-11-17 US claimed
US-4402849-A DIELECTRICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-09-06 US claimed
EP-0031021-B1 TETRAHYDROQUINAZOLINES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL DISPLAY ELEMENT MERCK PATENT GmbH (DE) 1983-05-18 EP claimed
EP-0031021-A1 Tetrahydroquinazolines, process for their preparation, liquid crystalline dielectrics containing them and electro-optical display element MERCK PATENT GmbH (DE) 1981-07-01 EP claimed