Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124019 | 1.00 | ALOX15 (0.50) | ALOX15HSD17B10PNMTCD44MAOB | |
| Hydrogen Sulfide SCHEMBL27951535 | 0.98 | ALOX15 (0.48) | ALOX15HSD17B10PNMTCD44MAOB | |
| Hydrochloric Acid SCHEMBL4630968 | 0.98 | ALOX15 (0.48) | ALOX15HSD17B10PNMTCD44MAOB | |
| SCHEMBL3757557 | 0.88 | ALOX15 (0.41) | ALOX15HSD17B10PNMTCD44MAOB | |
| Pyridine SCHEMBL19995258 | 0.88 | ALOX15 (0.46) | ALOX15HSD17B10PNMTCD44MAOB | |
| SCHEMBL1828551 | 0.79 | — | — | |
| SCHEMBL30668800 | 0.79 | — | — | |
| SCHEMBL2041999 | 0.79 | — | — | |
| SCHEMBL5474126 | 0.79 | ALOX15 (0.48) | ALOX15HSD17B10PNMTCD44MAOB | |
| SCHEMBL379799 | 0.79 | CD44 (0.52) | ALOX15HSD17B10PNMTCD44MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099510-A1 | RESILIENT MARKER COMPOUNDS | MINTON, TREHARNE & DAVIES LIMITED (GB) | 2026-05-15 | — | — | WO | disclosed |
| EP-4739393-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | Merck Sharp & Dohme LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4739393-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | Merck Sharp & Dohme LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| WO-2026087753-A1 | PROCESS FOR REDUCING A NITROGEN-CONTAINING FUNCTIONAL GROUP | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2026-04-30 | — | — | WO | disclosed |
| CN-111655695-B | Substituted furopyrimidine compounds as PDE1 inhibitors | 达特神经科学有限公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4522759-A1 | REDUCTION OF NITROGEN-CONTAINING GROUPS IN A TARGET COMPOUND USING A BIOCATALYST | Oxford University Innovation Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| US-20250082639-A1 | ALPHA POLYGLUTAMATED METHOTREXATE AND USES THEREOF | L.E.A.F. HOLDINGS GROUP LLC | 2025-03-13 | — | — | US | disclosed |
| US-20250026759-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME LLC (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2025014788-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME LLC (US) | 2025-01-16 | — | — | WO | disclosed |
| WO-2025014788-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME LLC (US) | 2025-01-16 | — | — | WO | disclosed |
| CN-116005178-A | Synthesis method of 1,2-dihydro quinazoline compound | 淮北师范大学 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022225699-A9 | POLY(TETRAHYDROQUINAZOLINE) AND DERIVED CARBON AEROGELS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2023-03-23 | — | — | WO | disclosed |
| CN-115819170-A | Method for synthesizing chiral dihydroquinazoline compound | 山西警察学院 | 2023-03-21 | — | — | CN | disclosed |
| CN-115745910-A | Chemical compound | 安塔比奥公司 | 2023-03-07 | — | — | CN | disclosed |
| WO-2022225699-A2 | POLY(TETRAHYDROQUINAZOLINE) AND DERIVED CARBON AEROGELS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022171013-A1 | TETRAHYDROQUINAZOLINE COMPOUND | 南京明德新药研发有限公司 | 2022-08-18 | — | — | WO | disclosed |
| WO-2022125412-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125412-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-16 | — | — | WO | disclosed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| US-20220062284-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220062284-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | ACIN1, REV1, NFATC1 | ALOX15 3464/4885HSD17B10 3149/4885PNMT 2611/4885 |
| US-20250026759-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | ACIN1, REV1, NFATC1 | ALOX15 3464/4885HSD17B10 3149/4885PNMT 2611/4885 |
| US-20250082639-A1 | ALPHA POLYGLUTAMATED METHOTREXATE AND USES THEREOF | MTX1, MTX2, IFNG | ALOX15 1790/4885HSD17B10 3961/4885PNMT 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.