Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763876 | 0.89 | ST14 (0.46) | ST14IDO1ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL19361317 | 0.89 | ALDH1A1 (0.49) | ST14SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL6679010 | 0.86 | ST14 (0.50) | ST14IDO1NPC1RAB9ANOS1 | |
| SCHEMBL1286912 | 0.86 | KDM4E (0.56) | ST14IDO1SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL6682640 | 0.86 | ST14 (0.50) | ST14IDO1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL17198821 | 0.84 | NPC1 (0.55) | ST14IDO1SMN1; SMN2CYP1A2NPC1 | |
| SCHEMBL18401315 | 0.84 | ST14 (0.49) | ST14IDO1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3916731 | 0.84 | TAAR1 (0.52) | ST14IDO1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14012684 | 0.84 | ST14 (0.49) | ST14IDO1SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10310202 | 0.84 | NPC1 (0.51) | ST14IDO1SMN1; SMN2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703825-B2 | Compounds, use thereof as medicaments, and method of preparation thereof | UNIVERSITE DE LORRAINE (FR) | 2014-04-22 | — | — | US | disclosed |
| US-20110184070-A1 | NOVEL COMPOUNDS, USE THEREOF AS MEDICAMENTS, AND METHOD OF PREPARATION THEREOF | UNIVERSITE HENRI POINCARE NANCY 1 (FR) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184070-A1 | NOVEL COMPOUNDS, USE THEREOF AS MEDICAMENTS, AND METHOD OF PREPARATION THEREOF | CYP11B2, NPM1, B2M | ST14 4327/4885IDO1 996/4885ITGB3 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.