Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PCNA | P12004 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311547 | 0.88 | MEN1 (0.48) | EPHX2KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL19133112 | 0.86 | EPHX2 (0.43) | EPHX2ALDH1A1SMN1; SMN2TSHRCA1 | |
| SCHEMBL10304153 | 0.81 | MEN1 (0.56) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL24307290 | 0.81 | TSHR (0.43) | EPHX2KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL21762771 | 0.81 | MEN1 (0.39) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL16081529 | 0.81 | MEN1 (0.39) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL8956669 | 0.81 | MEN1 (0.39) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL22845257 | 0.80 | EPHX2 (0.48) | EPHX2THRBMEN1KMT2A | |
| SCHEMBL13864736 | 0.80 | EPHX2 (0.48) | EPHX2THRBMEN1KMT2A | |
| SCHEMBL16081648 | 0.79 | MEN1 (0.42) | KDM4EALDH1A1SMN1; SMN2TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998706-B2 | Pyrimidine nucleobases | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-16 | — | — | US | disclosed |