Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13864736 | 1.00 | EPHX2 (0.48) | EPHX2CES2CASP2EPHX1MEN1 | |
| SCHEMBL13864743 | 0.93 | CASP2 (0.49) | EPHX2CES2CASP2EPHX1LPAR1 | |
| SCHEMBL13864739 | 0.93 | CASP2 (0.49) | EPHX2CES2CASP2EPHX1LPAR1 | |
| SCHEMBL13864735 | 0.93 | CASP2 (0.49) | EPHX2CES2CASP2EPHX1LPAR1 | |
| SCHEMBL13864762 | 0.93 | CASP2 (0.49) | EPHX2CES2CASP2EPHX1LPAR1 | |
| SCHEMBL19133112 | 0.86 | EPHX2 (0.43) | EPHX2CASP2MEN1KMT2ALPAR1 | |
| SCHEMBL22374761 | 0.84 | FAAH (0.38) | EPHX2MEN1KMT2AFAAHTLR2 | |
| SCHEMBL13311547 | 0.84 | MEN1 (0.48) | EPHX2MEN1KMT2A | |
| SCHEMBL22340558 | 0.83 | KDM4E (0.48) | EPHX2CASP2MEN1KMT2AFAAH | |
| SCHEMBL22340820 | 0.82 | CASP2 (0.64) | EPHX2CASP2EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263935-A1 | HCK DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |