Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396522 | 1.00 | BRD4 (0.61) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL6759202 | 0.85 | BRD4 (0.60) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL108857 | 0.84 | BRD4 (0.63) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL28472394 | 0.83 | BRD4 (0.61) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL1737254 | 0.83 | BRD4 (0.61) | BRD4NPC1RAB9ATDP2PDE4A | |
| SCHEMBL29870373 | 0.83 | BRD4 (0.61) | BRD4NPC1RAB9ATDP2PDE4A | |
| SCHEMBL3369457 | 0.82 | BRD4 (0.57) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL31471103 | 0.81 | BRD4 (0.60) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL16505732 | 0.81 | BRD4 (0.60) | BRD4TDP2PDE4ACYP1A2TSHR | |
| SCHEMBL31453471 | 0.81 | BRD4 (0.60) | BRD4TDP2PDE4ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092033-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Avistone Biotechnology Co., Ltd. (CN) | 2025-03-20 | — | — | US | disclosed |
| EP-4458818-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Avistone Biotechnology Co., Ltd. (CN) | 2024-11-06 | — | — | EP | disclosed |
| CN-116003406-B | Heteroaryl ring nitroxide compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2024-01-23 | — | — | CN | disclosed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | disclosed |
| US-20230416256-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARAMCEUTICA NV (BE) | 2023-12-28 | — | — | US | disclosed |
| EP-4244224-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2023-09-20 | — | — | EP | disclosed |
| WO-2023125803-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125803-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2023-07-06 | — | — | WO | disclosed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-1136556-A | Aromatic group substituted W-amino alkyl amide and alkyl amide | CIBA GEIGY CO LTD (CH) | 1996-11-27 | — | — | CN | disclosed |
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |
| EP-0361791-B1 | Azacyclic derivatives useful as medicaments | SMITHKLINE BEECHAM FARMA (IT) | 1995-11-08 | — | — | EP | disclosed |
| EP-0249707-B1 | PICOLINIC ACID DERIVATIVES AND HERBICIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5089507-A | Also diuretic; long lasting, side effect reduction | DR. L. ZAMBELETTI SPA (IT) | 1992-02-18 | — | — | US | disclosed |
| EP-0447704-A1 | N-Acylated azacyclic compounds, processes for their preparations and their use as medications | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1991-09-25 | — | — | EP | disclosed |
| US-4931087-A | Picolinic acid derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0361791-A2 | Azacyclic derivatives useful as medicaments | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1990-04-04 | — | — | EP | disclosed |
| US-4832729-A | Picolinic acid derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0249707-A1 | Picolinic acid derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416256-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | NFKBIA, IKBKB, NFRKB | BRD4 875/4885CA12 4821/4885CA1 4775/4885 |
| US-20250092033-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | CYP19A1, WEE1, WEE2 | BRD4 4417/4885CA12 3089/4885CA1 1793/4885 |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | KDM5C, KDM5B, KDM5A | BRD4 75/4885CA12 3916/4885CA1 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.