Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870373 | 1.00 | BRD4 (0.61) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL4914014 | 0.90 | KDM4E (0.61) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL31037820 | 0.90 | KDM4E (0.61) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL7356194 | 0.90 | ALDH1A1 (0.61) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL14840493 | 0.90 | TSHR (0.58) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL14840457 | 0.87 | TSHR (0.54) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL2801546 | 0.87 | BRD4 (0.56) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL12158504 | 0.87 | BRD4 (0.56) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL8407020 | 0.87 | ALDH1A1 (0.64) | BRD4TSHRHTTALDH1A1HSD17B10 | |
| SCHEMBL21639387 | 0.86 | TSHR (0.53) | BRD4TSHRHTTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3654929-B1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | OREAL (FR) | 2024-05-29 | — | — | EP | claimed |
| CN-115322350-A | Degradable bio-based polyester and preparation method and application thereof | 苏州瀚海新材料有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-112142729-B | Mefenapyr intermediate and preparation method and application thereof | 山东润博生物科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| WO-2021127642-A1 | SELECTIVE VALORIZATION OF BIOMASS SUGARS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-24 | — | — | WO | claimed |
| CN-112142729-A | Mefenapyr intermediate and preparation method and application thereof | 山东润博生物科技有限公司 | 2020-12-29 | — | — | CN | claimed |
| EP-3654929-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2020-05-27 | — | — | EP | claimed |
| EP-3236919-B1 | PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION | OREAL (FR) | 2019-10-16 | — | — | EP | claimed |
| EP-2861206-B1 | COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A BINDING POLYMER, METHOD THEREFOR, AND USE THEREOF FOR TREATING HAIR | OREAL (FR) | 2019-06-12 | — | — | EP | claimed |
| WO-2019016153-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING A PYRIDINEDICARBOXYLIC ACID DERIVATIVE AND A HYDROXYSTILBENE | L'OREAL (FR) | 2019-01-24 | — | — | WO | claimed |
| EP-3386476-A1 | COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD | L'Oréal (FR) | 2018-10-17 | — | — | EP | claimed |
| US-5124458-A | Reacting a dialkyldichlorosuccinate with a dehydrohalogenating agent, treating the reaction product with ammonia, treating the new reaction product with an unsaturated aldehyde or ketone | AMERICAN CYANAMID COMPANY (US) | 1992-06-23 | — | — | US | claimed |
| US-5118809-A | Mixing with ammonium salt and unsaturated aldehydes or ketones | AMERICAN CYANAMID COMPANY (US) | 1992-06-02 | — | — | US | claimed |
| EP-0461403-A1 | Process for the preparation of dialkyl pyridine-2,3-dicarboxylate and derivatives thereof from dialkyl dichlorosucciante | AMERICAN CYANAMID COMPANY (US) | 1991-12-18 | — | — | EP | claimed |
| EP-0461401-A1 | Process for the preparation of dialkyl, pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichloromaleate | AMERICAN CYANAMID COMPANY (US) | 1991-12-18 | — | — | EP | claimed |
| EP-0461402-A1 | Process for the preparation of substituted and unsubstituted 2,3-pyridinedicarboxylates from chloromaleate or chlorofumarate or mixtures thereof | AMERICAN CYANAMID COMPANY (US) | 1991-12-18 | — | — | EP | claimed |
| EP-0456504-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-11-13 | — | — | EP | claimed |
| EP-0415767-A2 | Process for preparing pyridine carboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |
| EP-0220518-B1 | PREPARATION OF SUBSTITUTED AND DISUBSTITUTED PYRIDINE-2,3-DICARBOXYLATE ESTERS | AMERICAN CYANAMID COMPANY (US) | 1991-02-06 | — | — | EP | claimed |
| US-4723011-A | ALPHA-HALO-BETA-KETOESTERS, ALPHA, BETA UNSATURATED KETONE OR ALDEHYDE, AMMONIUM SALT | AMERICAN CYANAMID COMPANY (US) | 1988-02-02 | — | — | US | claimed |
| EP-0220518-A2 | Preparation of substituted and disubstituted pyridine-2,3-dicarboxylate esters | AMERICAN CYANAMID COMPANY (US) | 1987-05-06 | — | — | EP | claimed |