SCHEMBL12403308

SCHEMBL12403308

NCCN(CCN)CCNCC(O)COc1ccc(C(c2ccc(OCC(O)CNCCN(CCN)CCN)cc2)C(c2ccc(OCC(O)CNCCN(CCN)CCN)cc2)c2ccc(OCC(O)CNCCN(CCN)CCN)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ADRB3 P13945 7/20 0.47
▸ ADRB1 P08588 6/20 0.47
▸ ADRB2 P07550 4/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ OPRM1 P35372 1/20 0.47
▸ OPRD1 P41143 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ ABCB1 P08183 2/20 0.42
▸ ATM Q13315 1/20 0.41
▸ MAPT P10636 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12403297 0.81 MAPK1 (0.52) KDM4EALDH1A1CYP1A2MAPTHTT
SCHEMBL18506359 0.79 ADRB3 (0.60) ADRB3ADRB1ADRB2MEN1OPRM1
SCHEMBL16314627 0.75 SMN1; SMN2 (0.53) KMT2AKDM4EALDH1A1CYP1A2ATM
SCHEMBL17038023 0.74 ADRB3 (0.71) ADRB3ADRB1ADRB2MEN1OPRM1
SCHEMBL17038022 0.74 ADRB3 (0.71) ADRB3ADRB1ADRB2MEN1OPRM1
SCHEMBL13343921 0.73 KDM4E (0.38) ADRB3ADRB2KMT2AKDM4EALDH1A1
SCHEMBL11376334 0.72 KMT2A (0.56) ADRB3ADRB1ADRB2MEN1OPRM1
SCHEMBL10838546 0.72 ADRB3 (0.66) ADRB3ADRB1ADRB2MEN1KMT2A
SCHEMBL20436123 0.72 ADRB3 (0.54) ADRB3ADRB1ADRB2MEN1OPRM1
SCHEMBL18506367 0.72 ADRB3 (0.61) ADRB3ADRB1ADRB2MEN1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 — — US disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 — — US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 — — US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 ADRB3 1082/4885ADRB1 826/4885ADRB2 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback