Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403308 | 0.81 | ADRB3 (0.47) | KDM4EALDH1A1MAPTHTTCYP1A2 | |
| SCHEMBL12403459 | 0.79 | ALDH1A1 (0.52) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL16314627 | 0.79 | SMN1; SMN2 (0.53) | KDM4EALDH1A1LMNAMAPTTSHR | |
| SCHEMBL1101870 | 0.77 | HTT (0.60) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL10077719 | 0.77 | HTT (0.60) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL12403146 | 0.77 | GAA (0.64) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL12403447 | 0.76 | ALDH1A1 (0.55) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL14345644 | 0.73 | GAA (0.50) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL1101566 | 0.73 | HTT (0.55) | MAPK1KDM4ETDP1GAAALDH1A1 | |
| SCHEMBL26326216 | 0.73 | AR (0.53) | MAPK1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985424-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES INC. (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985424-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES INC. (US) | 2011-07-26 | — | — | US | disclosed |
| WO-2007149501-A2 | PROCESS FOR PREPARING DENDRITIC POLYMERS USING MICROWAVE ASSISTED SYNTHESIS | DENDRITIC NANO TECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298006-A1 | Dendritic Polymers With Enhanced Amplification and Interior Functionality | MYD88, TLR3, TMEM97 | MAPK1 4174/4885KDM4E 3988/4885TDP1 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.