Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | DNM1L | O00429 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14775731 | 0.99 | PDE10A (0.53) | PDE10AHSD11B1MCHR1NAPEPLDTSHR | |
| SCHEMBL12408684 | 0.83 | HSD11B1 (0.47) | PDE10AHSD11B1MCHR1NAPEPLDTSHR | |
| Hydrochloric Acid SCHEMBL2178719 | 0.83 | HSD11B1 (0.46) | PDE10AHSD11B1MCHR1NAPEPLDTSHR | |
| Hydrochloric Acid SCHEMBL2178300 | 0.82 | PDE10A (0.53) | PDE10ANAPEPLDALDH1A1NPC1RAB9A | |
| SCHEMBL2181157 | 0.80 | PDE10A (0.47) | PDE10AHSD11B1MCHR1NAPEPLDALDH1A1 | |
| SCHEMBL2181159 | 0.80 | PDE10A (0.47) | PDE10AHSD11B1MCHR1NAPEPLDALDH1A1 | |
| SCHEMBL2180456 | 0.71 | PDE10A (0.71) | PDE10AHSD11B1NAPEPLDDNM1L | |
| SCHEMBL2180464 | 0.71 | PDE10A (0.71) | PDE10AHSD11B1NAPEPLDDNM1L | |
| SCHEMBL2178866 | 0.70 | PDE10A (0.65) | PDE10A | |
| SCHEMBL2178858 | 0.70 | PDE10A (0.65) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166135-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-07-07 | — | — | US | disclosed |
| WO-2010030027-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166135-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | PDE10A, PDE3A, PDE3B | PDE10A 1/4885HSD11B1 813/4885MCHR1 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.